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		TOP articles published in Nature Index Contribution of LAS in NATURE INDEX Journals. See more		Ni-catalyst in [3+2] indole cycloadditions with cyclopropanes New nickel-catalyzed regio/diastereoselective indole and cyclopropane [3+2] cycloaddition published in *Molecules* 2024. See more



		Established the "Biotechnology Network Brazil-Italy-Chile for the Production of Molecules of high value-added products" IProject granted by CNPq-Brazil 2024 . See more		Ni-catalyst in [3+2] indole cycloadditions with cyclopropanes New nickel-catalyzed regio/diastereoselective indole and cyclopropane [3+2] cycloaddition published in *Molecules* 2024. See more



		New CO2 fixation mediated by Guanidinium Iodide Salts Development of new family of Catalysts for production of epoxides published in New J. Chem. 2024. See more		New Air-stable Co(III) and Cr(III) as Catalysts for CO2 and Epoxides New complexes with high catalytic activities without co-catalysts and solvent-free published in Inor. Chem. 2024. See more



		New Monothiosquaramide-Pd and -Fe complexes in asymmetric hydrogenations Development of new family of Catalysts for hydrogenations published in Asian J. Org. Chem. 2024. See more		Biopolymer-Based Hydrogel/Ag-NPs for Antimicrobial Applications IUnique structural properties in new synthesis of nano-scaled materials published in Polymers 2023. See more



		Established the "Platform for Respiratory Virus Detection" by Multiomics in Talca Innovative techniques in developing next-generation swab tests for Viruses of Special concerns. See more		Detection of SARS-CoV-2 in nasal swabs using MALDI-MS Innovative technique to detect COVID-19 was published in *Nature Biotechnology* 2020 (IF 68,1). See more



		Enantioselective Imine Reduction of Dihydro-β-carbolines by Fe-TSQ Catalyst First Iron-Catalyst for asymmetric obtention of tetrahydro-β- carboline frameworks was published in Org. Lett. 2022. See more		Brown seaweed-derived alginic acid: A new catalyst for Pictet-Spengler reaction New process to tetrahydro-β- carboline and tetrahydroisoquinoline frameworks was published in Asian J. Org. Chem. 2022. See more



		Detection of organic gunshot residues from human hands using DSA-TOF-MS Innovative technique to detect gunshot residues was published in *J. Mass Spectrom.* 2022. See more		Salivary proteome of aphthous stomatitis reveals the participation of vitamin metabolism, nutrients, and bacteria was published in Sci. Reports 2021. See more



		TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines Facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline" was published in RSC Adv. 2021. See more		New methallyl nickel complexes Nickel complexes in alkene activation: a combined DFT, ESI-MS and chemometric approach was published in Catal. Sci. Technol. 2021. See more



		Detection of SARS-CoV-2 in nasal swabs using MALDI-MS Innovative technique to detect COVID-19 was published in *Nature Biotechnology* 2020 (IF 36,5). See more		Detection of SARS-CoV-2 in nasal swabs using MALDI-MS and multivariate analysis Biotyper approach to detecte COVID-19 was published in J. Virol. Methods 2020. See more



		Detection of SARS-CoV-2 in nasal swabs using MALDI-MS Innovative technique to detect in a fst way COVID-19 was published in *Nature Biotechnology* 2020 (IF 36,5). See more		RID inhibited chemokine in human breast cancer cell line MDA-MB-231 Inhibition of chemokine expression in human breast cancer cell line MDA-MB-231 was published in Mediators Inflamm.2020. See more



		New Organocatalyst Approach to Chiral Spirooxindole Active Compounds Thiosquaramide organocatalyst applied for high enantioselective synthesis published in RSC Adv. 2020. See more		Development of eco-friendly polyurethane foams based on Lesquerellafendleri (A. Grey) oil-based polyol New polyurethane foams was published in Eur. Polym. J.2020. See more



		Copper (II) as catalyst for intramolecular cyclization and oxidation of (1,4-phenyl ene)bisguanidines to benzodiimidazole-diylidenes Plausible key mechanistic steps involving organic and inorganic species were intercepted by ESI-MS in *J. Catal.* 2020. See more		Novel lipophilic analogues from 2,4-D and Propanil herbicides: Biological activity and kinetic studies New lipophilic herbicides as potential alternative to traditional formulations *Chem. Phys. Lipids* 2020. See more



		Ru(II)-catalyzed regioselective hydroxymethylation of β-carbolines via C-H functionalization and mechanism by online ESI-MS/MS screening The scope of this reaction and the elucidation of the mechanism was published in J. Org. Chem. 2019. See more		Hydrogel/Silver Nanohybrids Mediated by Tunable-Size Silver Nanoparticles for Potential Antibacterial Applications Studies to synthesize low-disperse AgNP and bacterail activity was published in Polymers 2019. See more



		Substitution effects of NaCl by KCl and CaCl2 on Lipolysis of Salted Meat A combination of NaCl and KCl salts can be a good alternative for reducing the NaCl in salted meat was published in Foods 2019. See more		Comparison of the Oxidative Stability and Antioxidant Activity of Extra-Virgin Olive and Colliguaya integerrima and Cynara cardunculus Oils Studies to use2 new seeds as nutritionally edible oils was published in Antioxidants 2019. See more



		Simple approach for cleaning up TCA from whisky and wine by using PANI The provision of efficient materials for the removal of TCA improves the purification processes employed in beverage production and was published in Austral. J. Grape Wine Res. 2019. See more		Synthesis of New 1,2,3-Triazolo Conjugates for lung cancer: DNA Intercalation and Cytotoxic Studiess Compounds clearly showed apoptotic features indicating that inhibition of cell proliferation by apoptosis published in *JBCS* 2019. See more



		Inhibition of IL-2 Production by Novel Small Molecules using Build-ing Blocks from Chiral Reduced Chalcones and a Substituted Proline" The scope of this protocol using Noyori catalyst was published in Molecules 2018. See more		Rational Development of a Newl Hydrogel as a pH-Sensitive Controlled Release System for Nifedipine Studies to rationalize nanodelivery of new nanomaterials in Polymers 2018. See more



		Novel Alkylimidazolium Ionic Liquids as an Antibacterial Alternative to Pathogens of the Skin and Soft Tissue Infections Published in Molecules 2018. See more		Intermolecular stabilization in new Pd(II) 2-iminopyridine derivatives complexes and reactivity towards alkenes Published in J. Organomet. Chem. 2018. See more



		FONDECYT REGULAR 2022 GRANTED FONDECYT REGULAR was granted for the period of 2022-2026. The National Fund for Scientific and Technological Development (FONDECYT) is the main public fund of the Government of Chile to promote basic scientific and technological research in all areas of knowledge. See more		Established new collaboration with Montpellier University, INRA-France Studies to rationalize selectivities for the polyphenol adsorption in the process of treating rosé wines by PVPP and other resins are ongoing with Dr. Cédric Saucier (Univ. Montpellier). See more



		Polyaniline Based Materials as a Method to Eliminate Haloanisoles in Spirits Beverages In this research, the abilities of two polyanilinebased materials (PANI-EB and PANI-ES) were evaluated as potential fining agents to eliminate TCA and TBA was published in Ind. Eng. Chem. Res. 2018 See more		MALDI-Ion Mobility for enantiomeric determination The use of MALDI traveling wave ion mobility spectrometry - mass spectrometry (MALDI-TWIMS-MS) for stereoselective structural analysis of solid phase synthesis was published in J. Mass Spectrometry 2018. See more



		New experimental-computational study to rationalize dendrimer interactions with organic compounds Recently work published in Int. J. Polym. Mat. Polym. Biomat. See more		Dr. Santos recognized by Argentinian Mass Spectrometry Society In the last meeting of Argentinian Mass Spectrometry Society in Cordoba, Dr. Santos was distinguished as Honorary Member of Soc. Argentina de Espetrometría de Masas. See more



		A new multicomponent reaction for direct synthesis of primary gama-nitroamides Recently work published in RSC Adv. explores the multicomponent reactions as a special class of the one pot reactions for the synthesis of GABA analogues. See more		New Polymer for Removal of Wine Phenolics in Food Chemistry Among the polymeric agents, PVPP is one of the most used, but lacks of selectivity and has a limited pH range. Therefore, the aim of this study was the synthesis of a new polymer, P-NIOA, for removal of phenolic compounds, as a potential agent for the fining of wine. See more



		Fast detection of pathogens in salmon farming industry Piscirickettsia salmonis and Caligus rogercresseyi are highly transmissible pathogens that cause high mortality in farmed salmonids... See more		Fast detection of Piscirickettsia salmonis in Salmo salar serum through MALDI-TOF-MS profiling Piscirickettsia salmonis is a pathogenic bacteria known as the aetiological agent of the salmonid rickettsial syndrome and causes a high mortality in farmed salmonid fishes. See more



		Fast Detection of Listeria monocytogenes through nanohybrid quantum dot complex A new nanohybrid compound was developed for the optical detection of Listeria that was based on nanocompound functionalized with an auxotrophic cofactor (lipoic acid) and quantum dots.... See more		On-bead MALDI-MS monitoring of solid-supported N-acyliminium ion reactions A new solid-support resin allows chemical reactions to be quickly monitored on solid support with no sample preparation by using on-bead matrix-assisted laser desorption/ionization-mass spectrometry analysis. See more



		Licensing Granted Patents Patents from United States Patent Office developed in the lab are under commercialization with Winery companies. US 8,927,042 B1 and US 8,883,239 B2 See more		A new multicomponent reaction for direct synthesis of primary gama-nitroamides A mechanistic pathway proposed for screening new reactions was employed in the published article in RSC Advances. See more